"significant invention" is a correct and usable expression in written English.
You can use it when you want to emphasize the importance of an invention. For example: "The invention of airplanes was a significant invention that forever changed the way we travel."
Why? -What do you think could be the most significant invention of the next generation?
Why or why not? -What do you think is the most significant invention made by a historic tinkerer?
However, this ever-evolving historia Britanniae does not mean that the Union's story is devoid of points of significant invention.
In 1899, the bicycle was such a significant invention for women, in terms of changing their clothing and the literal liberation from the house".
He did that first by means of the manifesto, perhaps the single most significant invention, or appropriation, of his chequered career.
It's interesting to note that the only significant invention in "Toys in the Attic" is the dialogue, which, as Joan Mellen points out in "Hellman and Hammett," her eminently readable 1996 study, was helped along by the writer Dashiell Hammett, Hellman's companion for many years, who also suggested part of the plot.
Many of our most significant inventions are pure tools, with no scientific method behind them.
One of his most significant inventions was a method of extracting silver from lead ore.
Highlight the subject's life work, significant inventions and the impact of his work on future generations.
Mr. Ceruzzi noted the "utter improbability and unpredictability" of having one of the most significant inventions of the 20th century come to life from such a seemingly obscure origin.
He added that the "utter improbability and unpredictability" of having one of the 20th century's most significant inventions spring to life at a little electronics shop in Albuquerque had prompted many people to search for other sources.
