Sentence examples for significant interest given from inspiring English sources

The role of genetic variation in modulating expression of the different members of heat shock protein families remains unresolved but is of significant interest given evidence of heritability and disease association.

The presence of modified lysine residues within multiple functional domains of PABP1, two of which were subject to differential acetylation and methylation (Lys and Lys), was of significant interest, given their ability to confer divergent functional properties.

Here, we examine the genetic diversity of human RNase 8, a subject of significant interest given the existence of functional pseudogenes (coding sequences that are otherwise intact but with mutations in elements crucial for ribonucleolytic activity) in non-human primate genomes.

However, McDowell said Murphy's remarks were of "significant public interest", given that IBRC was owned by the taxpayer.

Our findings are also of significant practical interest given that propranolol is a widely used drug in different settings, and is currently being considered as a potential treatment for post-traumatic stress disorder in military and rescue service personnel.

The molecular mechanisms that lead to glaucoma are not well established but are of significant biomedical interest given that glaucoma is a leading cause of blindness worldwide, and early-onset myocilin glaucoma accounts for ∼4% of glaucoma cases, primarily afflicting children [1].

"The US is not a claimant in the South China Sea, but we have significant interest there given its role in the global economy". Vietnam and the Philippines have sought to deal with the dispute in international forums.

To identify candidate genes associated with the significant markers, we conducted a survey of the genes present in the vicinity of the significant markers with a particular interest given to auxin- and kinases-related genes because genes of these families have already been shown to play a role in determining root cone angle.

Amplification or deletion of genes involved in the RB signalling pathway were seen in 60% (18 of 30) of metastases, which is of interest given the significant activity of CDK4 inhibitors in other cancers [ 26, 27].

Although some of the genes thought to be significant under the LRT test without the Bonferroni correction were no longer deemed significant results, they are still of interest given their phenotypes.

However, the strong and statistically significant effect observed for p,p′ -DDT (OR 5.4; p < 0.01) is of more interest given the sample size.