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Upgrading from a traditional soil spatial database, consisting of a single GIS layer of polygons and basic attributes, to a modern soil information system has required significant informatics resourcing.
Furthermore, NGS platforms usually produce very short reads (e.g. 35 100 bp); accurate de novo assembly of such short reads poses a significant informatics challenge.
This technique relies on multiplexed sample preparation followed by massive parallel sequencing and requires a significant informatics component for analysis [ 6].
The Department of Biomedical Informatics at the University of Utah, one of the leading informatics centers in the U.S. [ 15, 16], was selected for its significant informatics expertise, the availability of an existing clinical data repository and for its well-developed resources in both the clinical and research domains.
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Finally, phenotyping the patients to determine efficacy or drug toxicity requires significant medical informatics algorithm development.
The institute will soon occupy five buildings in Washington's central Dupont Circle neighborhood, with room for administrators, visiting scientists, and a significant in-house informatics program.
We need significant efforts in informatics, analytic methods development, meta-dimensional data integration, data sharing, data visualization, and strategies for bringing actionable biology into healthcare.
The resulting requirement to invest significant resources into custom informatics support for genome sequencing projects remains a major impediment to the accessibility of high-throughput sequence data.
In order to maximise the utility of cancer imaging, the oncology and imaging communities have devoted significant resources to developing informatics tools that allow both clinicians and researchers to store, utilise and share cancer images in more effective ways.
We aim to leverage Duke's world renowned faculty, cutting edge informatics research, and significant investments in Health Information Technology to create an academically rigorous and rich educational environment.
In fact, the latter task is a significant research topic in biomedical informatics research, since many different systems for automatically indexing and searching the biomedical literature have been developed over the last few years.
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