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The phrase "significant increases" is correct and usable in written English.
It can be used when discussing notable or substantial growth or rise in a particular context, such as statistics, sales, or performance metrics. Example: "The company reported significant increases in revenue over the last quarter, indicating strong market demand."
Exact(57)
— significant increases in defense spending.
Significant increases above that level are simply not affordable.
*Private groups report significant increases in areas like accounting fraud.
Both eruptions followed significant increases in low-frequency earthquakes.
Some companies report significant increases in short-selling of their stocks after such deals.
In recent weeks, they again posted significant increases in anticipation of the genome announcement.
They showed significant increases in delinquencies and foreclosures from 2004 and 2005 loans.
Only two of the publicy funded museums contacted by the Observer reported significant increases.
Strikingly, significant increases were seen among the poorest and the wealthiest.
Similar(2)
Nakuru and Amboseli show non-significant increases.
Including the unknowns also showed non-significant increases (Table 6).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com