Significance Analysis of Microarrays (SAM) analysis identified 1252 probe sets which detect significant gene expression changes throughout CAM development (>2-fold, FDR<5%).
Released compacted DNA produced significant gene expression in vitro, although at lower levels than freshly compacted DNA.
In all cases, significant gene expression differences were assessed using linear models and moderated t statistics (R package: limma, function: lmFit) [63].
In the mouse, intravenous injection of a luciferase expression plasmid complexed with ppTG1 or ppTG20 led to significant gene expression in the lung 24 hours after injection.
To integrate significant gene expression data from our transcriptome analysis into the diverse MapMan tools, we generated a dataset including Affymetrix probe_ids and average fold-change data of japonica over indica.
The most significant gene expression among them was that of ferritin genes, as the availability of Fe in cells would be deduced from the expression change of ferritin genes.
The underlying innate immune response is driven by significant gene expression changes in each cell, and recent work has provided novel insights into the gene regulatory mechanisms that mediate such transcriptional changes.
"There are rapid (within two hours of start of practice) and significant gene expression changes... during a comprehensive yoga program," the research team writes in the study.
Determination of significant gene expression change was done as previously described [46].
Further, there are significant gene expression differences between fetal and neonatal fibroblasts [28].
Following normalization one-way analysis of variance was performed for each gene to identify statistically significant gene expression changes.
