Messenger RNA transport has emerged as a significant mechanism for regulating gene expression.
Methylation of genomic DNA represents a significant mechanism for regulating tissue-specific gene expression.
First, the dissociation of transcription factors and epigenetic regulators observed upon chromatin condensation could indeed be significant for down-regulating the somatic cell transcription network, but only in the context of a rapid cell cycle leading to a relatively higher amount of time spent in M-phase.
Primary candidates for regulating genes are genes having significant correlated changes in their mRNA expression levels following copy number alterations.
Current industrial controllers use PLCs for regulating the belt speed of the tunnel, which leads to conservative set-points and consequently significant operational cost and frequent over-freezing.
On Capitol Hill, where federal and state officials testified on Monday at a Senate hearing on the mutual fund industry, lawmakers have begun to call for significant changes in regulating the industry -- which is in its greatest turmoil since it came under federal oversight more than 60 years ago.
The dramatic inability of the prkaca-L173A and prkaca-F327A mutants to maintain viability in the tpk null strain may indicate that residues that undergo structural rearrangement may play a more significant role in regulating nucleotide binding for PKA activity.
Of these three hubs, the MapK/ERK pathway most probably plays a significant role in regulating ABCD3 expression for two reasons.
MSCs in bone marrow represent 1 in 100,000 nucleated cells, but they play a significant role in regulating the niche for hematopoietic stem cells and immune homeostasis and hypothetically can differentiate into cartilage, bone, and adipocytes [ 1].
Apoptosis, a highly structured and orchestrated process, performs a significant role in regulating cell number for the growth and homeostasis of tissues by eliminating aged, damaged, and unwanted cells [ 7, 8].
