Earthquakes are serious natural disasters that can result in significant fatalities and economic loss.
Large outbreaks of hand, foot, and mouth disease have been reported in the Asia Pacific region over the last few years and resulted in significant fatalities.
The Chilean earthquake of February 27, 2010 and the Samoa earthquake of Sep 29, 2009 caused significant fatalities due to the resulting tsunamis, and the Sumatra tsunami of 2004 took the largest toll of human life on record, with approximately 228,000 casualties attributed to the waves.
This particular type of earthquake is especially hazardous to tall buildings, which could lead to significant fatalities in downtown areas.
Both EHDV-1 and EHDV-2 have been responsible for numerous large-scale epizootics in wild ungulates (especially white-tailed deer), sometimes with significant fatalities [20].
Influenza has a substantial impact on global health, and it accounts for significant fatalities annually worldwide (Nair et al, 2011).
The extremely severe HFMD (ESHFMD) mainly caused by EV71 with severe neurologic clinical symptoms and significant fatalities [ 8– 10], that had caused serious public health concerns.
Prior studies reported that EV71 might cause severe neurologic diseases or significant fatalities, and most severe HFMD cases are EV71 positive [ 13, 14].
SAB was associated with significant case fatality both in ESRD patients and in population controls.
Despite widespread availability of antimicrobial therapy, tuberculosis continues to carry a significant case fatality rate, estimated at 4 7%% in notified HIV-uninfected cases [ 1].
