Sentence examples for significant exacerbation from inspiring English sources

Hammar et al. [ 13] investigated 124 patients before and after treatment with GnRH analogs and concluded that there was a significant exacerbation of gastrointestinal symptoms after treatment, and abdominal pain was still exacerbated at 5-year follow-up.

However, mCPP did not produce any significant exacerbation of obsessive compulsive symptoms in the patient group.

However, significant exacerbation of the headache has also been reported when these drugs are used [26].

We demonstrated that Epoetin delta and Darbepoetin alfa produced no significant exacerbation of pre-retinal neovascularisation, even at the highest dose.

There was a small but statistically significant exacerbation of lavage fluid protein 24 hours after LPS in animals exposed to 100 ppm CO, consistent with a recent study showing that 50 ppm CO alone induced small increases in protein levels in lavage fluid of rats [33].

They also exhibited a significant exacerbation of the normal gap/overlap effect, consistent with 'sticky fixation'.

Secondary end points included significant exacerbations requiring systemic corticosteroids, all exacerbations, and changes in FEV1.

A selection bias may have been inadvertently created for patients well enough to participate or more motivated to participate in trials, or who had not had any significant exacerbations of medical conditions that would prevent inclusion in a clinical trial.

Since IL-1β is known to contribute to osteoarthritis pathology, the Col1-IL1βXAT Cre inducible model was used to model osteoarthritis and when these animals were crossed with APP/PS1 mice and injected with Cre to induce chronically elevated IL-1β expression, there were significant exacerbations of Aβ deposition and associated microglial activation [ 64].

A significant temporary exacerbation in the glycaemic control was found after the Great Hanshin-Awaji Earthquake.

The primary outcome measure was the annualized rate of significant asthma exacerbation episodes, those requiring a doubling of baseline inhaled corticosteroid dose, during the steroid stable phase.