Sentence examples for significant epigenetic modification from inspiring English sources

Histone acetylation is a significant epigenetic modification in embryo development and nuclear reprogramming.

The apparently normal mucosal field of patients presenting with neoplasia has evidently undergone significant epigenetic modification.

DNA methylation is the most significant epigenetic modification in eukaryotic genome which plays a key role in many existing cellular pathways including apoptosis, cell adherence, DNA repair, and cell-cycle control and during the development of cancer [ 12– 12].

97 Therefore, it is unclear if significant epigenetic modifications are the cause or consequence of disease (or autoimmunity) and studies to establish the temporal origins of epigenetic changes may shed light on the timing of environmental risk factors.

DNA cytosine methylation is an important epigenetic modification that has significant effects on a variety of biological processes in animals.

Histone acetylation is an important epigenetic modification.

DNA methylation is one of the most important epigenetic modifications.

We show that Shh expression is rapidly regulated both in vivo and in vitro in response to thyroid hormone, accompanied by significant epigenetic histone modifications within upstream regions of the Shh gene.

DNMT inhibitor such as 5-azacytidne also plays a significant role in epigenetic modification.

Our previous work suggested that the PB element allows transgene expression without significant silencing or epigenetic modification among generations (Ding et al., 2005).

Another significant epigenetic process is chromatin modification.