Sentence examples for significant endpoints from inspiring English sources

Fig. 1 Clinically significant endpoints of hospital-acquired (HAP) and ventilator-associated pneumonia (VAP).

A number of disease outcomes can be used as surrogate markers of clinically significant endpoints, and a number of adverse effects may serve as surrogate markers.

Three significant endpoints emerged from the Heine trial [ 22] which were included in the model as treatment effects.

Most recently, a trial of early, low-dose steroids in ARDS showed improvements in gas exchange without improvements in clinically significant endpoints [ 75].

74 So far, it has not been possible to demonstrate whether treatment with sulfonylureas decreases significant endpoints, such as cardiovascular events, in the long term.

The data derived should feed into group numbers used for definitive studies (e.g., therapy experiments) in order for experimental time frames and statistically significant endpoints to be established.

Waist circumference was also statistically significantly decreased in the exenatide group and increased in the insulin glargine group (table 2), resulting in a significant endpoint difference between treatments (p < 0.001).

Stable disease is recognised as a significant endpoint in the evaluation of clinical benefit associated with many targeted agents, and a focus on only conventional complete or partial responses assessed in the conventional manner using RECIST[ 41 ] may underestimate efficacy and risk discontinuation of the development of active new agents[ 42 ].

The effect of the principal factors was not always significant for endpoints that focused on components of the snapshot response.

When compared with chlorthalidone, the amlodipine group had a higher rate of heart failure, and the lisinopril group had higher rates of CVD, stroke, and heart failure – all statistically significant secondary endpoints.

We believe the latter is a more significant clinical endpoint.