Sentence examples for significant dosage from inspiring English sources
The phrase "significant dosage" is correct and usable in written English.
It can be used in contexts related to medicine, pharmacology, or any situation where the amount of a substance is being discussed and is considered important or noteworthy. Example: "The study revealed that a significant dosage of the medication led to improved patient outcomes."
There were significant dosage dependent differences in bee infection and survival rates.
20 mg is still a significant dosage, making it nearly impossible to taper off the drug.
There was a significant dosage effect (trend) in the association between the A allele of rs10838524 and rapid cycling (P = 0.0076) and this allele increased the risk for rapid cycling both in a homozygote and a heterozygote form (that is dominant model) compared to ABD controls (OR = 1.79, P = 0.0081) (Table 2).
The mechanisms of damage to fertility may be similar for chemotherapy and for a significant dosage of radiation to the gonads [129,130].
However, not a single region was identified but rather several smaller regions on HSA21 that agglomerate a large amount of significant dosage effects.
We further analyzed human and mouse studies separately and found 182 significant dosage effects using only human and 107 dosage effects using only mouse data.
However, there were significant dosage-dependent increases in apoptosis both in R482Q/+ and R482Q/R482Q animals (p<0.001, non-parametric trend test), and in Fbxw7 +/− and Fbxw7 −/− animals (p=0.010) compared with wild-type (see online supplementary figure S3A, C).
In total, 1773 genes showed a significant gene dosage effect and for 1727/1773 (97.4%, indicated by red dots in Fig. 5B) the gene dosage effect was in the expected direction (positive linear regression slope: more copies correlated with more expression and less copies correlated with less expression).
The ANOVA results enunciated that the significance of the parameters is as follows (the most to the least significant): Cu/TiO2 dosage > time > initial phenol concentration.
Statistical analysis performed on detected probesets revealed a significant gene dosage effect on gene expression for all but two genes (Fig 3).
Using survival tree analysis and/or joint analysis of multiple variants, Wu et al. suggest there is a significant gene dosage effect and a polygenic analytical approach should be used to predict clinical outcomes.
