In addition to neural tube defects, mouse embryos exposed to VPA show a significant disorientation of the neuroepithelium; in particular, defects were observed in the forebrain region, including the flattened appearance of telenchephalic hemispheres.
Of the 22 cases that met criteria for incapacitation, 21 cases contained enough information to document when the patient was first observed in an incapacitated state, with incapacitation defined as the presence of clinically significant disorientation, ataxia, or sedation such that the patient would not have been able to seek assistance on his own.
Immediate effects of significant exposure include disorientation, loss of continence, coma, and death.
It evidences a significant distribution of azimuthal disorientation for the first graphene plane compared to the SiC lattice.
A Grade One concussion usually does not involve a loss of consciousness, Grade Two can cause a momentary lapse of consciousness, and Grade Three generally features significant memory loss and disorientation.
As assessed by the AQ, difficulties with orientation to time, repetition of questions and statements, difficulties in managing finances, and visuospatial disorientation were all significant predictors of aMCI as diagnosed by an expert in memory disorders.
Eight BPRS items: Somatic concern, Anxiety, Hallucinations, Self-neglect, Disorientation, Emotional withdrawal, Tension and Distractability showed no significant associations with any of the NPI-21 scores.
A significant shrinkage in the low temperature range was attributed mainly to a disorientation process in oriented noncrystalline chains.
Significant effects were found between the three individual differences with respect to disorientation, learning performance and attitudes in the HLS that provided no instructional aids, whereas no such effects were found for the other HLS version.
We also found that patients with diplopia had lower scores on the 'far distance estimation' and 'visual disorientation' domains compared with patients without diplopia, but there were no significant differences on the 'social contact and appearance' scales.
Animal [ 87] and human [ 88, 89] studies have shown that prolonged continuous flow caused significant changes in the aortic wall, including medial degeneration, smooth muscle cell (SMC) disorientation and depletion, elastic fiber fragmentation and depletion, medial fibrosis and atherosclerotic changes [ 89].
