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The ministry said Iran was facing "difficulties concerning medication supplies".
In combination with other health issues (e.g. limited mobility and managing diabetes) this mild memory problem caused significant difficulties and concern.
One of the most significant obstacles is the difficulty concerning circulating miRNA normalization.
Insofar as the banker's tips to his brother are concerned, Salman's Newman personal benefit argument will likely face significant difficulties.
The hazards, safety concerns and radiowaste generation associated with using open-source radioactive isotopes can present significant difficulties, the use of hot cells and escalated costs in radioanalytical laboratory research.
One in five experience "significant difficulties".
Upon leaving, staff running the programme estimated that 80% of care leavers still faced significant difficulties.
As Ragan puts it, they are children with "autism which causes them severe and significant difficulties".
Moreover, it has significant difficulties with changing illumination conditions.
System designers experience significant difficulties in programming these platforms.
Ofwat, Ofgem, Ofcom and the FCA understand the "significant difficulties" facing consumers.
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