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It made a significant difference to the Mirror's headline figure of course.
Even the smallest of changes to the wording of a religion question can make a significant difference to the responses.
However, even if you don't change any of the pre-sets, it does make a significant difference to the sound.
"Everyone knows that Setanta has made a significant difference to the money available to the FA.
Replacing Nick Clegg with Vince Cable could make a significant difference to the Liberal Democrats' chances in a new general election.
Of more immediate concern to City fans is whether Sterling alone can make a significant difference to the club's chances of finishing ahead of Chelsea.
The only significant difference to the original demo is those thudding introductory drums in place of an acoustic guitar, a decision taken by producer Owen Morris.
The reality is that having women in decision-making positions makes a significant difference to the issues brought to the table.
Despite the rise in sales and profits, Wiener said the use of zero-hours contracts had not made a significant difference to the bottom line.
Witty accepts that his stance may not win him friends in other drug companies, but he is inviting them to join him in an attempt to make a significant difference to the health of people in poor countries.
They mostly cover core costs, and focus is on supporting underfunded charities that can make a significant difference to the lives of disadvantaged people by helping them to play a fuller role in the community.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com