Despite significant data suggesting improved patient outcomes with the adoption of these pathways, development and implementation has been limited in the neurosurgical population.
Until now, no significant data suggested that SIH is caused by decreased CSF secretion or generalized CSF hyperabsorption [28].
Significant data suggest that overt hyperglycemia, either observed with or without a prior diagnosis of diabetes, contributes to an increase in mortality and morbidity in hospitalized patients.
Although the clinical benefits of adjuvant 5-FU/LV-based treatment are significant, data suggest that patients generally prefer oral therapy to intravenously administered treatments [ 11].
18 They were able to obtain significant data suggesting that chlorogenic acid not only retards the absorption of fats from the intestine but also activates fat metabolism in the liver.
A study published by L.D. Edmonds, P.M. Layde, and J.D. Erickson in the July August 1979 issue of the Archives of Environmental Health found no significant data suggesting an effect of noise on fetal development in pregnant women who lived near airports.
Although not significant, this data suggests that tumour subtype was not the cause of better prognosis for the CTNNB1 nuclear tumours.
Although the increases in hypoxia-induced lipid peroxidation and 8-oxo-dG lesions were statistically significant, our data suggests that these changes may not have been large enough to induce a biological impact.
Although the anti-angiogenic properties presented by DHPM on the CAM assay were not statistically significant, our data suggests a marked reduction in vessel convergence toward tumor cell implantation and vessel thickness.
Given that D L c o was not significant the data suggest that the mode of inheritance can be non-dominance.
Based upon these epidemiologic observations, as well as significant preclinical data suggesting a cancer prevention and therapeutic anti-cancer role for metformin in certain malignancies, a National Cancer Institute of Canada prospective randomised trial in early breast cancer has been initiated (Parulekar et al, 2011).
