Sentence examples for significant clinical issue from inspiring English sources

Imatinib intolerance is a significant clinical issue which leads to dose reduction or discontinuation.

Emergence agitation is a significant clinical issue during recovery from general anaesthesia.

As the number of different AAI designs has increased, Device Switches have become a significant clinical issue.

Since mealtime insulin dose is a major determinant of postprandial glycemic control, improving the insulin algorithm is a significant clinical issue.

The lack of robust information available to guide clinical decisions in the subgroup of patients with T1aN0 or T1bN0 HER2+ tumours remains a significant clinical issue.

Despite technology-driven improvements in cancer radiotherapy (RT) [ 1], radiation toxicity remains a significant clinical issue that influences treatment outcome, patient quality of life and survivorship.

In many cases these involved significant clinical issues such as incorrect name, strength or active ingredient of a medicine on the packaging or errors in the product information leaflet in relation to administration or toxicity.

Currently, ovarian carcinoma presents significant clinical issues, as the 5 year survival rate for all stages and types is 44%%, while stage IV invasive ovarian carcinoma has a 5 year survival rate of 17%% [ 41].

The selection of candidates for BRCA germline mutation testing is an important clinical issue yet it remains a significant challenge.

Their findings represent a significant advance in our understanding of metastatic dormancy, an extremely important clinical issue that remains understudied.

Residual and significant postinfarction left ventricular (LV) dysfunction, despite technically successful percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI), remains an important clinical issue.