Sentence examples for significant clinical importance from inspiring English sources

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Differentiation of active inflammation from fibrosis is of significant clinical importance both for the prediction of therapy response and clinical outcome of ILD.

Bacterial Oxacillinases (OXAs), genetically being extremely diverse and highly versatile in hydrolyzing antibiotics of different classes, holds utmost significant clinical importance.

P. aeruginosa is a pathogen of significant clinical importance because it can elicit a severe pneumonia in affected individuals.

As aging is associated with progressive decline in organ function, elucidating the complex pathways controlling the rate of aging is of significant clinical importance [1].

We also extended the utility of our system to trap A. fumigatus, a spherical yet smaller (∼3 µm diameter), fungal pathogen of significant clinical importance [37].

The fact that CMA analysis performed on DNA from uncultured blood cells was able to improve the detection of low level mosaicism missed by cytogenetic analysis, is of significant clinical importance, especially for the diagnosis of genital ambiguity.

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The nephrologists' survey confirmed that the adverse effects scoring system provided moderate-to-significant clinical importance (3.1 ± 0.75 with maximum score of 4.0) for the assessment of the 18 adverse effects in renal transplant recipients.

Although the mean difference between the pressures obtained via the catheters inserted in the aVCI and VCS (0.9 mmHg) were statistically significant, the clinical importance of this difference may not be important.

However, even if the differences concerning axillary node involvement as a function of tumour size were statistically significant, their clinical importance is limited: the difference in the risks of nodal involvement adjusted for tumour size (estimated for an 18-mm tumour diameter) was only 2% (P=0.01) between SG 1976 1990 and SG 1991 1999.

The goal of the article is to provide a clearer understanding of how melatonin and its related analogs interact with melatonin receptors with the hope of developing important tools and agents of significant clinical and scientific importance.

The peptide TOC has been extensively studied with other chelators (DOTA, NODAGA, DTPA, DFO) in both imaging and therapeutic modalities, and has significant clinical and commercial importance (Lin et al. 2013; Eisenwiener et al. 2002; Dumont et al. 2011; Fani et al. 2011; Ugur et al. 2002).

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