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"This was a significant challenge to his leadership".
Still, the square and its problems pose a significant challenge to the center's audience-building efforts.
This is a significant challenge to the traditional political methodology of social democracy.
"This is a significant challenge to which we expect the BBC to make a significant response".
The events created the climate for a significant challenge to Museveni's grip on power.
"This represents a significant challenge to Palm," said Michael Gartenberg, an analyst for the Gartner Group, a research firm.
Nationally, the game is viewed as the Tigers' last significant challenge to finishing the regular season undefeated.
But today's opposition motion calling for a statement of her objectives posed a significant challenge to the Tory party management.
Tragically, Iran's government appears to have driven back the most significant challenge to its repressive rule since the 1979 revolution.
Haley said he thought stucco posed the most significant challenge to Hardie's improving its market share in coastal regions.
By raising the costs of the old rules, social change poses a significant challenge to conservative religious groups.
More suggestions(16)
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significant problem to
major challenge to
substantial challenge to
large challenge to
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sizable challenge to
remarkable challenge to
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notable challenge to
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com