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The notion that the heart harbours a population of Sca1+ PDGFRα+ mesenchymal progenitors able to generate both fibroblasts and adipocytes aligns with the hypothesis that this population is the most significant cellular source of fibrofatty infiltration in AC.
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In combination, these characteristics create a significant challenge to determining the exact cellular source of circulating miRNA.
Moreover, our observations with respect to the cellular source of these cytokines also implicate significant changes in the airway macrophage population and their involvement in the pathophysiology of allergic airway responses in sheep.
Combined, these sources of reactive species can cause significant cellular and tissue damage that the cell responds to in several ways.
Next experiments aimed to evaluate the potential cellular source of inflammation in EACH hearts.
Next, we asked what is the cellular source of the ECM-related transcriptional response.
Basal (saline-treated) TLR4 levels reflected the cellular source of TLR4.
Immunogenic peptide-based vaccines can raise significant cellular immune responses.
Significant cellular uptake as revealed by fluorescence imaging makes them suitable for cell labeling studies.
It is shown that the junctional source is negligible compared to the cellular source.
Both vaccines raised significant cellular responses for Gag, Pol, and Env.
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