To date, P. alecto miRNAs have not been studied yet are likely to play significant roles in important cellular functions including immunity, apoptosis, the cell cycle, inflammation, and DNA repair.
Despite the lack of understanding of the physiological function of anhydromuropeptide product, LT enzymes must play a significant cellular role.
On the other hand, free fatty acids (FFAs) are not only essential nutritional ingredients but also significant to many cellular functions through receptors of FFAs [19].
Herein, we demonstrate that each of the differentially regulated proteins (scripted in bold), is biologically relevant and has been shown to play statistically significant role/s in cellular functions associated with lipid metabolism.
In addition, cell growth, proliferation, and the cell cycle were identified to be the most significant molecular and cellular functions.
The 5 most significant molecular and cellular functions identified were cellular development, cellular growth and proliferation, cellular function and maintenance, cell death, and lipid metabolism [Additional file 7].
The most significant molecular and cellular functions, along with the number of up- and down-regulated genes observed in each function, are presented in Figure 1.
Significant molecular and cellular functions identified included gene expression, proliferation, cell cycle, cell death, and cytoskeletal organisation (supplementary material Table S3).
The analyses produced 20 significant molecular and cellular functions (See Additional File 7 – Figure S4) that are significantly enriched in both gene sets.
