Exact(4)
However, more cases are needed to establish an accurate pattern of the cell infiltrate in malignant lesions, and the most significant cell type(s).
Nevertheless, there was a highly significant cell type and treatment × day × cell type × section interaction effect both for PPC and SI (Table 1).
Therefore, expression analysis of DSC3 shows a significant cell type specific pattern of expression, which is limited to cells of epithelial origin, including breast epithelium.
While, on average, the effect size of all FDR significant cell type specific differences is quite small (0.067%), over 14% (n = 37,399) and 1% (n = 2693) of significant loci exhibit DNA methylation differences greater than 20 and 50%, respectively.
Similar(56)
Indeed, Rpn13 is not a constitutive proteasome subunit, since only a fraction of 26S proteasomes contain Rpn13 [9], and we observed significant cell type-specific differences in the expression pattern of the protein in certain tissues which might explain the seemingly contradictory data from cell lines about Rpn13 function [9], [10].
Enhancers show significant cell type-specific signatures whereas promoter states are more stable across cell types.
Interestingly, various studies noted significant cell type-specific differences in CagAPY levels during infection of human cell lines.
Detailed analysis of nucleosome positioning with micrococcal nuclease (MNase) combined with parallel sequencing clearly showed significant cell type-specific differences in nucleosome organization between granulocytes and T-cells [ 11].
To determine the proportion of PP-decreased DEGs that may be accounted for by these cell types, PP-decreased DEGs were inspected one-by-one, and each was assigned to one of the eight significant cell types.
Indeed, mitochondrial proteome has significant cell-type differences, allowing mitochondria to serve in a highly adaptive fashion to the cellular specific functional requirements [27].
As shown in Figure 1, there is a significant, cell-type specific background fluorescence signal which mainly derives from the wall of the plant cell.
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