Doolan said other significant causes of childhood blindness include cataracts and glaucoma.
Legal challenges and casework "issues" are cited as the most significant causes of delays in their deportation.
Mental health and coronary heart disease were the first two frameworks to be produced, as they are significant causes of illness and disability.
Although the companies talk of tackling the threat that climate change poses to food security, the agroindustrial food system is one of the most significant causes of it, contributing a third of all manmade greenhouse gas emissions.
A denial of rights at work, including the minimum wage, holiday and sick pay, are significant causes of poverty, campaigners say.
Heat waves may span several days to several weeks and are significant causes of weather-related mortality, affecting developed and developing countries alike.
BMA President Elect, Sir Al Aynsley-Green said: "Exposure to alcohol before birth is one of the most significant causes of childhood brain damage, learning disability, poor behaviour and even criminality, affecting up to one in every 100 infants.
Krueger concludes that "rather than economic conditions, the hate crimes literature points to a breakdown in law enforcement and official sanctioning and encouragement of civil disobedience as significant causes of the occurrence of hate crimes".
We need to quit worrying about cellphones ("Do Cellphones Cause Cancer?" by Siddhartha Mukherjee) and focus our collective energy on the known, significant causes of cancer: tobacco, sun exposure, hepatitis, etc., while continuing to research other possible causes.
These are significant causes of risk for businesses in developing countries all over the world.
Human noroviruses and hepatitis A virus (HAV) are considered as epidemiologically significant causes of foodborne disease.
