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In lymphocytes, immune response was the most significant category associated with increasing expression.
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In each zone comparison, "development", "collagenous" probe sets and "molecular transport" were deemed the most significant categories associated with BP, CC, and MF, respectively (Figure 4A).
All significant gene categories associated with the Biological Processes domain of the Gene Ontology (GO) Consortium[27] were determined, using a significance threshold of p<0.05.
Transcriptome analysis showed significant overrepresented categories associated with the plant defense response to pathogen infection in necrotic symptom-exhibiting Arabidopsis hybrids.
δThe table shows partial listing of representative significant εGO categories associated with biological processes (30 among 99).
δThe table shows partial listing of representative significant εGO categories associated with cellular components (36 among 83).
No significant categories were associated with Up-late genes.
This analysis showed significant enrichment in GO categories associated with cell wall metabolism, chromosome organization and biogenesis, and mitotic recombination.
We also found significant changes in functional categories associated with basic cellular processes, such as cell growth, proliferation and cytoskeletal structure.
To identify segments with shared function as well as coexpression, we tested each segment for significant enrichment of GO Slim categories associated to its genes.
Within the top ten most significant gene set overlaps, multiple functional categories associated with development were strongly enriched within our differentially methylated gene list.
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