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The use of rational design in the development of a biocatalyst, although widely successful, suffers from a few shortcomings, the most significant being that the metabolic pathway for the production of the target must be elucidated.
This community had serious grievances, the most significant being that educated young muhajirs could not get jobs because of imposed quotas.
The worsening national performance follows changes to the GCSE league tables, the most significant being that only a pupil's first attempt at sitting a GCSE paper counts towards a school's overall pass rate.
Of course, as Joseph Heller noticed, anyone who didn't want to risk his life was by definition not crazy, but there were other conflicts at work, the most significant being that the army wasn't interested in making people better, it was interested in making them well enough to go back and fight again.
Many good musicals have been inspired by lesser material, but Fierstein's additions to the already corny story — the most significant being that Winston is now a gay man, and one who is surprisingly uninhibited for the Bronx in 1953 — feel contrived and tacked on.
There are subtle differences between RSSCloud and PuSH, the most significant being that RSSCloud just notifies your feed reader there is something new, while PuSH actually sends the content with the notification via so-called fat pings.
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Industry competition comes in several forms, the most significant being companies and agencies that choose to do business development and training in-house rather than outsourcing.
Several conclusions can be drawn from these studies, the most apparent being that significant differences can exist at the molecular and cellular level in humans and rodents, and that rodent-based studies may benefit from complementary approaches using human cells of the appropriate type.
Intraindividual variation was not significant for seven out of nine volunteers (with one of the two that were significant being border-line) and interindividual variation among all 27 individuals remained highly statistically significant (χ26=60.05, P<0.001).
However, shared ownership currently presents some significant legal flaws for the purchaser – not the least being that there is actually no 'shared ownership' at all.
To human beings that's just intuitive.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com