One study on these diets that showed significant parent-reported and objective improvement, using tests for communication, cognitive, motor, verbal and social skills, was rated as having a high risk of bias.
High-dose Y-DOTATOC targeted radiotherapy is a well-tolerated treatment which has significant clinical benefit and objective response for NETs [ 53].
If a significant relationship between subjective and objective methods to evaluate eating quickly can be confirmed, then the subjective method can be widely and reliably used in many fields.
Furthermore, in a small phase 1 clinical study using VEGF gene transfer, all patients had significant reduction in angina and objective evidence of reduced ischemia was documented using dobutamine 99mTc-sestamibi SPECT imaging.
We found significant improvements in subjective and objective image quality indices when low-dose CT images were reconstructed with a commercially available iterative reconstruction technique, namely adaptive statistical iterative reconstruction (GE Healthcare, GE Medical Systems, Milwaukee, WI) when compared with low-dose images reconstructed with filtered back projection.
In that cross-sectional study, we showed significant correlations between FC and objective markers of SSc GI disease, that is, cineradiography and micronutrient deficiency [ 3].
More recently a randomised controlled trial of individual cognitive behavioural therapy intervention for insomnia, delivered by a psychologist, demonstrated significant improvement in subjective and objective sleep indices for patients with chronic neck and back pain [ 26].
In this study we confirm our earlier results showing significant correlations between FC and objective signs of SSc GI disease as determined by cineradiography and testing for micronutrient deficiency.
There were also no significant differences in PFS and objective response between arms A (sc-IL-2/sc-IFN α/po-13cRA) and B (arm A plus inhaled-IL-2), and between arms C (arm A plus iv-5-FU) and D (arm A plus po-Capecitabine).
Pijpe et al. reported observing a significant improvement in subjective and objective measures, including subjective reports of dryness, fatigue, and salivary flow, mainly in patients with early-onset disease and in only a few with pSS-associated MALT (mucosa-associated lymphoid tissue) lymphoma [ 11].
