Sentence examples for significant and key from inspiring English sources

A senior PSNI officer described the weaponry, which was found near a disused house on the outskirts of Lurgan, as "significant and key".

Corrigan, C. M. et al. Developing important marine mammal area criteria: learning from ecologically or biologically significant areas and key biodiversity areas.

Still, the sponsorship issue is significant and five key slots — worth around $15 million each — remain unfilled.

They are functionally significant and potentially key regulators of gene expression during skeletal muscle development [ 24– 29].

UNICEF's role in brokering partnerships among the various parties has been noted as significant, and a key support for the implementation of national policies at the local level.

The biogenesis of miRNAs is spatiotemporally regulated by various mechanisms [ 9], providing additional evidence that miRNAs are functionally significant, and potentially key regulators of gene expression during development [ 10- 15].

DMD 53 patients scored significantly lower in the MFM (D3: 66 ± 17% vs. 82 ± 13% for DMD 53 vs. DMD control), had significant lower handgrip and key pinch strength on both hands.

The TNF pathway was significant in CD only, and key components selected include two enzymes that are regulators of NF-κB signalling a negative regulator of NF-κB, the deubiquitinating enzyme CYLD [35] (rs7342715) and TNFAIP3 (rs7753394) both a deubiquitinating enzyme and a ubiquitin ligase [36].

Similarly, AKR1C3 is a promising target given its significant up-regulation in CRPC and key role reducing androstenedione to testosterone (Adeniji et al, 2013).

The significant increase in albumin, globulin and key proteins regulating the colloidal osmotic pressure of blood may be due to the reduction of water consumption and food intake during the winter.

"But we have to remember, differences in antibody yield that are statistically significant might not be biologically significant, and that's the key issue.