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Furthermore, a significant amount of active TGFβ1-containing CM of SCL-1 tumour cells (CMSCL) [ 12] resulted in formation of MFs as well.
There is about a 5-fold reduction in the proportion of particles that undergo fast, directed movements in these mutants, although there is still a significant amount of active transport in each case.
The localization of p38 did not change significantly under the conditions tested but there was a significant amount of active p38 present in the nuclei of the cells (Supplementary Figure S3A and B).
Similar(56)
Messenger RNAs for the A. thaliana enzyme were found in a variety of tissues that did not contain significant amounts of active enzyme suggesting the possibility of translational or posttranslational controls on methyltransferase levels.
The efficacy and versatility of this novel pair of co-expression vectors was successfully applied to the production of significant amounts of active DFF40/DFF45 heterodimeric protein complex in E. coli for detailed biochemical and structural studies.
This result indicated that sperm cells from Cre-expressing fathers did not transfer significant amounts of active Cre protein or mRNA to their offspring.
Importantly, only when CTLA-4 blockade or regulatory T-cell depletion were performed together with ablation, significant amounts of active OVA-specific T cells could be observed.
Not surprisingly, as significant amounts of active MMP-2 and MMP-9 (as well as other enzymes) are also present in skin organ culture fluid, fragments of other sizes were also detected.
(Significant amounts of active full-length protein could not be obtained upon expression in bacteria, consistent with work from Hirokawa on KIF1A motor protein [ Nitta et al., 2004].) Surprisingly, deletion of the CBD in the context of full-length KIF1C did not abolish binding to GST-Rab6A.
Thus, considering that it has been demonstrated that breast cancer cells may show the ability to synthesize a significant amount of biologically active prolactin [ 28], we may speculate on a potential relationship between lysozyme and prolactin.
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