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The data obtained before the manipulation were compared with data obtained after the manipulation to determine if significant alterations occurred.
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A number of alternative splicing events occurred in weaned calves relative to pre-weaning with the most significant alterations occurring on d 1 (Additional file 9: Table S9).
Controlled longitudinal studies of steroid profile during pregnancy are scarce, but according to available data, significant alterations occur not only in the production of progesterone and oestriol, but also in androgen concentrations.
In the amphibia the tripartite type of pectoral girdle made its first appearance; the coracoid represented by the ventral bar in the fishes became segmented into the anterior procoracoid and posterior coracoid, while the clavicle came in relation to the procoracoid No significant alterations occur in the suprascapula and the scapula.
It is implausible that genetic factors are responsible for this increase because it is unlikely that significant genetic alterations occurred during such a short time (10 years).
In 1295, however, a significant change occurred.
There is considerable heterogeneity of capillary response to radiation with respect to the time course and dose required for significant alterations to occur; however, the pattern of changes is similar among different tissues.
In the rat VDT user model, dramatic histopathological alterations occurred.
Some alterations occurred inside the lipid classes.
These results suggested that a significant biochemical alteration occurs in cells treated with paraquat for 24 h that irreversibly commits the cells to undergo cell death.
It could explain why certain layers of compact intrusive basalt still appear fresh: if there is no water circulating, no significant alteration can occur.
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