Sentence examples for significant alterations have from inspiring English sources
Significant alterations have been made to the underlying road network in the area.
In PILOnoSE animals non significant alterations have been observed both quantitatively and qualitatively, with no evident signs of neuronal suffering or degeneration.
Significant physical alterations have seemed largely impossible until very recently.
Other significant neurotransmitter alterations have been described during experimental sepsis, involving brain beta-adrenergic, gamma-aminobutyric acid, and serotoninergic pathways [40].
Results indicate the following: (1) significant hydrological alterations have been identified and alterations of precipitation extreme regimes are one of the pivotal factors triggering hydrological alterations of AMS, as abrupt changes of precipitation extremes occur is similar to that of the AMS in time and space.
Other significant neurotransmitter alterations have been described during experimental sepsis, involving brain beta-adrenergic, gamma-aminobutyric acid, and serotoninergic pathways [ 40].
The use of short term, primary cultures does not solve the problem because significant genetic alterations have been found after only a small number of passages in glioma cultures [ 30, 81].
No significant morphologic or topographic alterations have occurred in this muscle.
What alterations have you made?
The property, dating from 1775, has Grade II-listed status, which protects it from significant alteration, and has been owned by Colin Algate, a former managing director in the travel industry, for the past 20 years.
However, in cases 3 and 6, the tissue samples were acquired 53 and 31 months, respectively, prior to treatment; it is therefore unclear whether or not other biologically-significant alterations might have emerged closer to the time of treatment.
