Sentence examples for significant affinity for from inspiring English sources

Derivative 6j having diphenylamine moiety attached to nitrogen of thiazolidinone showed significant affinity for the M1 receptor binding.

Potential mechanisms include alterations to the pain-modulating dopaminergic system and carbergoline, an ergot derivative, also possesses significant affinity for certain subtypes of serotonergic and adrenergic receptors.

In addition, LY2428703 has high specific binding to brain homogenates displaceable only by mGluR1 antagonists and no significant affinity for other human mGluRs [10].

It was first developed for magnetic resonance imaging (MRI) applications as a chelator for gadolinium [6], but showed significant affinity for several other metal ions [7].

It was also observed that CST supported on PTFE or PE fibrils had a significant affinity for both cesium and strontium.

Herein we show that 3-chloropropanoic acid possesses significant affinity for the GHB receptor, has no affinity for GABA receptors, and cannot undergo metabolism to GABAergic compounds.

2008 Naronapride is structurally related to the chemical structure of cisapride, but devoid of significant affinities for other 5-HT receptors or the hERG channel.

While the functional relevance and specificity of the interactions remains to be fully understood (e.g. many 5hmC interacting proteins also have significant affinities for 5mC) these readers might recruit chromatin regulatory complexes to their targets and support activated transcription.

Hypothesis (a) was rejected on the basis of equilibrium saturation studies of [3H]citalopram binding, which revealed no significant affinity of DOM for the 5-HT transporter of rat brain membranes.

In this study, we could not see significant affinity of AGM for VEGF in a similar assay with human proteins (data not shown).

This may explain why we could not detect any significant affinity of the protein for ATP in vitro.