"In every one of these countries there are vital stories unfolding, stories of crucial significance that need to be told, so it's understandable that news organizations are accepting a certain level of risk," Mr. Simon said.
On the contrary, the historical process by which Western humanity came to understand art as "aesthetics" is so freighted with significance that it needs to be recognized as "one of the essential phenomena of the contemporary age" (QCT 116/GA5 75).
There are important caveats here — and the story is of such significance that we need to emphasize those caveats up high.
Speaking to the BBC, President Marie Louise Coleiro Preca said William's presence would give the 50th anniversary celebrations the "significance" that was needed.
But this strategy ensures a recurring cycle of armed conflict, a decision of such significance that all citizens need to be weighing it and considering it, not just a select few.
The realities of religious co-existence within this pluralistic society have long been the subject of academic debate (Glick, 1992; Soifer, 2009) and food, in particular, might be expected to gain a significance that went beyond physiological need.
However, the role of these anti-cytoplasmic antibodies, their translocation from the cytoplasm to the membrane surface, the mechanism of interaction with PLA2R, and their clinical significance are questions that need answers for a better understanding of the disease.
Today is World Water Day, an international day of significance that brings attention to the need for access to clean water.
Imagine if we saw something of grave significance that involved Russia, or China, or anybody else, interfering in our political process and we needed to understand the significance of that.
It is a racial version of a MacGuffin, a device to drive the plot that need not have real significance, and it functions perfectly for the purpose.
