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In addition, most of the traits - associated SNPs (TASs) were from novel genes without obvious biological significance relevant to the analyzed traits, and most of TASs were located in the intergenic regions or introns of coding genes.
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This technique is also used for evaluating the significance of relevant factors in experiments.
A sensitivity analyses were carried out to estimate the significance of relevant parameters and the existing calculation approaches.
However, since much of the underlying metabolic network is abstracted by the graph representation, there is a greater chance for graph-based approaches to return pathways without biological significance unless relevant parameters and heuristics are introduced to guide the search.
In 1976, in a case called Woodson v. North Carolina, the United States Supreme Court reasoned that "[a] process that accords no significance to relevant facets of the character and record of the individual offender … excludes from consideration in fixing the ultimate punishment of death the possibility of compassionate or mitigating factors stemming from the diverse frailties of humankind".
To determine the prognostic significance of relevant molecular and clinicopathological parameters, Cox univariate analyses were performed.
The Cox proportional hazards model was used for multivariate analysis to determine independent significance of relevant clinical covariates.
The final data were analyzed using the chi-square test and risk ratio to determine the significance of relevant parameters.
This raises the question whether the effect size is "clinically irrelevant" or the sample size too small to reach significance for relevant but small changes.
The other three variables retained the degree of statistical significance without relevant modifications in the magnitude of their effect on major infections (see Table 4).
Studies which examined the association between and asthma and ozone and NO2 as co-pollutants found inconsistent results with respect to statistical significance and relevant exposure period e.g., [ 12, 46, 50, 52, 57, 58].
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