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(3) For any pair of gene sets, such as gene sets A and B, the significance of node overlap Pnode_overlap is calculated.
Objectives of this study were to provide insight into the biologic significance of node metastases on clinical behavior and to assess the impact of systematic lymphadenectomy on progression-free and overall survival.
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The significance of nodes was tested by bootstrapping with 1000 replications.
The significance of nodes in the tree and the standard errors of the genetic distances were computed by bootstrapping 10,000 times.
In addition, this is one of the first papers that compared the prognostic significance of lymph node ratio to absolute number of positive nodes in patients with endometrial cancer.
Each node or each edge is attached with a weight that reflects the significance of the node or the edge.
The node size and color intensity are proportional to the hierarchical status and statistical significance of each node, respectively.
An assured diagnosis of lymph node micrometastasis determined by RT PCR is essential when performing SNNS, since the clinical significance of lymph node micrometastasis is also contentious (Ishida et al, 1997).
When testing the prognostic effects of lymph node, ER/PR, post-surgery adjuvant and APOA1 rs670 A/A carrying status in an adjusted model, the significance of lymph node and APOA1 rs670 A/A was stronger than of ER/PR and post-surgery adjuvant (Table 6).
Degree centrality is a quantitative network analysis technique to assess the relative significance of a node within the network.
Hashim et al. revealed that lymph node metastasis is predictive of a poor outcome among patients with PNETs [13], and Ge et al. recently revealed the prognostic significance of lymph node metastasis regarding non-functioning PNETs [14].
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