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However, "clinical significance of harm" did not remain in logistic models when statistically significant effects were considered.
The next two justifications appeal to the significance of harm, both to others and to oneself.
In the same article, however, authors suggest that another important factor must be considered: clinical significance of harm.
This may suggest that, in our sample, reporting harm in abstracts is driven more by statistics than by clinical significance of harm.
Similar(56)
But the restaurant's response wasn't enough for Brass, who said a satisfactory apology "would have included some recognition of the significance of the harm and acknowledgement that they want to make their restaurant and community safe for Indigenous women and families".
The amount and significance of overdiagnosis harm is particularly contentious [ 23].
Such a notion of harm limits the practical significance of the non-identity-problem to different degrees depending upon how the threshold is substantially defined (see Section 4 below).
Mark Cooper (Melbourne, Australia) put the trial results in context, further exploring the question of benefit versus harm, the significance of the renal findings, and the trial's clinical implications.
Such a model does not seem able to capture or even accommodate basic deontological notions like strict cutoffs between prohibited and permissible acts, the permissibility of an act depending on more than its expected consequences, or the significance of intended versus non-intended harms and benefits.
In defining the relevant threshold of harm we may also rely on considerations that reflect the significance of relative differences among future people or people who belong to different generations including the currently living.
There is a greater likelihood of harm to the patient in association with contaminated parenteral formulations, but the clinical significance of the problem is unknown, due to the lack of information related to their toxicity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com