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This significance is maintained by stratifying the 129 patients in the two age classes (<70, >70).
When the segment window contains more than one gene, the significance is maintained if the expression value of the over/under-expressed gene prevails over the others.
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DDDRValtpacing at the site of latest RV activation with AV delay minus 20 ms of intrinsic was associated with the greatest overall increase in CO including significant improvements over AAI pacing alone(Table 3 ), and this significance was maintained when directly compared with DDDRV apical pacing at the same AV delay: CO (5.8 ± 1.3 to 6.4 ± 1.7; P = 0.018).
when no covariates were accounted for (A), and the significance was maintained when covariates were included (B).
The size of the effects varies depending on the cutting point but relative effects as well as significance are maintained.
Statistical significance was maintained for the other five interactions following adjustment for potential confounders.
There was no differential association in men and women and significance was maintained when adjusting for the use of statins, hormone replacement therapy, ACE inhibitors and angiotensin receptor blockers all of which may affect levels of circulating EPC.
The main finding was significantly elevated mean plasma levels of anandamide (15.1±1.4 pmol/ml) and related NAEs in study subjects that carried the FAAH 385 A mutant alleles versus normal subjects (13.3±1.0 pmol/ml) with wild-type FAAH genotype (p = 0.04), and significance was maintained after controlling for BMI.
This significance was maintained using non-parametric statistics (Kruskal-Wallis, H = 34.6, p<0.001).
Using the Bonferroni correction the significance was maintained (P < α / 3; P <0.05/3; P <0.0167).
Significance was maintained even when the cut-off was reduced to 1.5 fold de-regulation (P < 0.001).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com