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The instructions bore tremendous significance in a city devastated by violence seven months ago.
But of even greater significance in a world of melting ice floes is control of the North West Passage.
A royal christening has perhaps a special significance in a country that has its own church.
The country of origin is of no significance in a global world.
In international law, nationality assumes significance in a variety of circumstances.
Speaking after the decision was made councillor Cox said the council needs to rethink their planning policy to deal with buildings which has emotional significance in a community.
In the case of Anaheim's Jean-Sébastien Giguère, there was both symbolic and practical significance in a goalie stick given to him by Patrick Roy.
Sherlock Holmes, the detective who was the mainstay of the publishing industry in his day, famously found significance in a dog's not barking.
But the presidents' visit underscores how a the once-tiny electoral bloc is taking on greater significance in a battleground state.
Any downturn in tax revenues of $20 billion to $56 billion would have almost no economic significance in a $2 trillion federal budget and a $10 trillion economy.
Todes argues that Pavlov's devotion to repeated experimentation was bolstered by the model of the factory, which had special significance in a belatedly industrializing Russia.
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