This plot reveals the amount of significance contained in SGoF against the intersection null, for each γ value.
Applying the same strategies for the 38 genes overexpressed in the fibrosis group, the functional groups with the highest levels of significance contained much fewer genes (2 to 7 per group, P < 0.049; Figure 5) which, surprisingly, were not related to matrix production/clearance.
Patterns of uncertain significance contain graphoelements/EEG patterns that resemble abnormal ones, but in most of the cases they are not associated with a pathologic process ("normal variants").
Among 13 profiles with significant numbers of associated proteins in Desiree, we found five profiles (number 26, 11, 9, 1, and 12 in order of significance) containing in total 156 proteins with lower abundance in the apoplast.
Based on manual survey of publications, we found that several previously implicated genes with clinical significance were contained in these two subnetworks.
The network with the highest significance also contained several cancer-related genes with high expression levels, including DSG2, PRKCA, PLA2G10, and Grp94.
The "Significance" panel contains all the parameters for the evaluation of the statistical significance of a motif subnetwork.
There were, however, a few remaining pathways that maintained their significance and contain genes that have an implicated role in Crohn's disease.
They are big in significance (like the ideas contained in a copy of the first printing of the Declaration of Independence, completed over July 4 and 5, 1776), and big in insignificance (like a 7-foot-1-inch-long bathtub custom built for the 340-pound, 6-foot frame of President William Howard Taft).
In order to facilitate comparisons to help determine the significance of temporal information contained in parameter contours as opposed to the statistical distributions of parameter values, another classification system based on Gaussian mixture models (GMMs) was set up.
As the result of these excavations and his ethnological investigations of the modern-day indigenous Huichol and Cora peoples of Nayarit, Furst proposed that the artifacts were not only mere representations of ancient peoples, but also contained deeper significance.
