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The genes which have significance connection between the biological response pattern (GI50) and the baseline gene expression, though may not be directly linked to the primary drug targets, they should be close to the pathway where the mechanism of action taking place.
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The continuous liquid-to-solid transition near Tg, the glass transition, has a profound significance in connection with classical applications of glasses.
We further lay out the perturbed inflammatory gene regulatory network to locate the significance differential connection of the key components.
For example, it could include study of the Notting Hill carnival, building insight into its historical significance and connections to the Caribbean, South America and Africa, the complex religious symbolism that underpins it, its economic, geographical and cultural impact, and its role in establishing London as a global city.
Indeed, an important contribution of this paper is to show the significance of connections between external economic shocks and internal political dynamics.
The functional significance and connections of the nbM were unknown until the 1970s when the cholinergic hypothesis in AD was proposed [ 9].
For stroke patients in the early stage, Pearson r correlations between VF performance and FC trended toward significance for connections between right caudate and right pars orbitalis (r = 0.37, P = 0.06, Pcorr = 0.13), and left superior temporal and right superior temporal regions (r = 0.33, P = 0.09, Pcorr = 0.06).
First explain what your example means (deductive reasoning), then explain its effect (inference) and its significance (making connections to the reader, to the context, to society, etc).
Scientists also point to a commonality between fat cells and immune-system cells, although the exact significance of the connection is unclear.
Law enforcement officials in the United States have played down the significance of the connection between Mr. Bayoumi and the two hijackers, saying there is no evidence that he was involved in the Sept. 11 plot.
Harmonielehre, John Adams's huge three-movement orchestral score first heard in 1985, takes its title from Arnold Schoenberg's important treatise on harmony, and this BBC National Orchestra of Wales performance was a reminder of the significance of the connection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com