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The monitoring boundaries for benefit, harm, or futility show the adjusted thresholds for significance (adjusted thresholds of the confidence intervals and the P-values) if a required information size has not been reached [ 25, 26, 47, 54].
In order to measure the association between the dependent and independent variables and its statistical significance, adjusted odds ratio, confidence intervals (CIs) for the adjusted odds ratio, Wald statistics and respective P-values were computed.
Proc Genmod, SAS version 6.14 (Statistical Analysis Systems , Inc Cary, NC), was used to perform a Wilcoxon test for a nonparametric analysis of covariance and significance adjusted for age and body size.
These studies achieved very high significance (adjusted HR, p < 0.0001) comparing death ten years after measurement of antecedent SUA, and as also noted by Levine[8], the strongest association between baseline SUA and cancer death was achieved in the older patient quartile.
Wave Ordinal: 1 to 9 The "wave" variable included in each one of the adjusted panel data models was used to observe trends in the propensity to receive HC of each type over the study time frame and the trend's statistical significance, adjusted by covariates.
The difference between male and female participants did not attain statistical significance (adjusted RR = 1.5, 95% CI = 0.41 5.14).
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** P values significant at a significance level adjusted by Bonferroni correction (0.05/17 = 0.0029).
Statistical significance was adjusted for multiple comparisons (significant differences, *p < 0.0125).
The p value is compared against the significance level adjusted for overall over-fitting error probabilities, where the adjusted α (k a ; k b ) = α/ MAX−k a ).
The level of test significance was adjusted to P<0.05.
A generalized family-wise error rate (gFWER) model is used to set a significance level adjusted for multiple testing.
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