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Despite the counterintuitive findings concerning their prognostic significance, active investigation of PI3K pathway blockade is currently ongoing and still could prove to be a curative strategy for PIK3CA mutant breast cancers.
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That 167 million is a fair bit lower than the 300 million Android devices that Eric Schmidt last week said had been activated overall — and does raise questions about what significance activation numbers have compared to active usage.
To investigate the biological significance of active RNAPII modifications (S7p+S2p+) and mRNA expression at active PRC targets (PRCa, n = 1,227), we mined ESC proteome data (Graumann et al., 2008) to determine whether PRCa genes are expressed at the protein level.
Actuator configuration and optimization are of great significance in active control of vibration and noise.
The achieved results of this research demonstrate the significance of active systems in machine tools.
Model predictions also highlight the significance of active bed width, rather than bed shear stress, as a fundamental ingredient in the prediction of the bed load rate and therefore, as an important morphological property to be modelled.
In the present study, we quantitatively investigated the functional significance of active conductance distribution pattern in the spatio-temporal spread of synaptic potentials over dendrites of an identified NSI in the crayfish central nervous system by computer simulation.
This is the first study examining the significance of active trigger points in subacute sciatica patients.
The existence and significance of active BAT in infants has been well reported.
Smoldering multiple myeloma (SMM) is an intermediate stage between monoclonal gammopathy of undetermined significance and active MM.
Although fairly reproducible, a disadvantage of JVCS is that it cannot provide any information regarding the significance of active lesions.
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