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Further non-parametric analysis of association signals may implicate additional genetic control of methylation levels.
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Candidate genes in these two causal regions may implicate aberrant glutamate signalling interacting with epigenetic factors in some ASD cases.
This led us to hypothesize that postprandial, gut-derived signals may be implicated in food-driven resetting of peripheral clocks.
The terms behaviour, cell signalling and response to an abiotic stimulus may implicate that part of these antisense transcripts were involved in synaptic processes or memory formation.
Smaller MMN response is a robust finding in schizophrenia and reduced amplitude may implicate impairment in prediction-error signalling.
The induction of some photosynthetic genes during the interaction between resistant Malus and E. amylovora may implicate light-sensing mechanisms in the induction of plant disease defense signaling.
Protein inhibitor of activated signal transducers and activators of transcription (PIAS 1, a regulator of cytokine signaling, may be implicated in the modulation of cellular events during carcinogenesis.
Here, we have shown several lines of findings that support that the IP3R-mediated Ca2+ signaling may be implicated in the calcineurin/NFATc signaling pathway although it is difficult to clarify whether IP3Rs may directly activate calcineurin during cardiogenesis.
Taken together, our data show that excessive activation of the HGF/Met system in development may result in cardiac damage and suggest that Met signalling may be implicated in the pathogenesis of cardiac disease.
This work suggests that the effect of aspirin on NF κB signalling may be implicated in the differential sensitivity of cancer types to aspirin-induced apoptosis.
Although upregulation of the HIF pathway may also occur as a result of a genetic alteration [ 23, 24], the nonmalignant nature of RA and OA suggests that hypoxic signaling may be implicated in the pathogenesis of these diseases.
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