This study can provide us much information, for example, in finding a target receptor, genes that encode key proteins, crosstalk between different signaling cascades, explanation for long term memory formation at the molecular level, and so on.
The need for "balanced" signaling provides an explanation for how a signaling system in which a single ligand binds to multiple receptor subtypes may develop naturally, although some of these active downstream pathways have diametrically opposite cellular effects [ 17].
"A culture of wealth without explanation" signals the "related culture of corruption".
Moreover, the influenza virus, which has been implicated in the etiology of schizophrenia, is capable of resetting the SCN, the ultimate processor of light signals, suggesting the explanation for chronological variability of incidence of schizophrenia.
Assuming that dancers' reduced self-motion perception is, indeed, reflected in a less well-developed cortical network for processing vestibular perceptual signals, then one explanation is of a cerebellar gating of vestibular signals of self-motion perception to the cortex.
This model that there are two cell death checkpoints during TNF signaling provides an explanation for the paradoxical observations that the TNF death signaling machinery is pre-existing in cells whereas the survival response is dependent on transcription, yet cells are largely resistant to TNF-induced cell death.
Amused, Nick said, "Who you?" "Mr. Trang, Rupertt whispered, more as a distress signal than an explanation.
The higher sensitivity to auditory signal provides an explanation for the increased prepulse inhibition ratio in KO animals and auditory cue-dependent classical fear conditioning.
Explanation: Signal sequences are characterized by a hydrophobic core, which sometimes is separately predicted as transmembrane domain.
This, together with the observed partially impaired progesterone signalling, provides an explanation for the defect in primary duct formation and side-branching in RIP140 KO mice.
