Sentence examples for signalling without from inspiring English sources

Activating mutations in BRAF, KRAS and NRAS can confer constitutive activation of ERK signalling without stimulation of their upstream signalling, thus EGFR inhibitors are not beneficial for cells with BRAF, KRAS, and NRAS mutations.

Captain Molloy then refused to carry out the order, signalling without cause that Caesar was unable to tack and then turning and sailing eastwards down the outside of the British fleet, rather than towards the enemy.

This confirms that rapamycin blocked mTOR signalling without influencing the upstream protein kinase AKT.

One of these compounds was shown to inhibit TGFβ signalling without displaying any significant cytotoxicity.

It is not obvious how we should discriminate computationally among different representations of EGFR signalling without imposing prior knowledge.

Our results demonstrate that Akt activation by any of these means may lead to less dependency on ErbB2/ErbB3 and Src signalling without inhibiting tumourigenesis.

"We have traffic signals without power.

Often we send these signals without being conscious of what we are doing.

How many samples are required to represent a given signal without loss of information?

The bition heightens anandamide signaling without producing reinforcing effects in primates.

LM11A-31 reached brain concentrations known to inhibit degenerative signaling without toxicity or induction of hyperalgesia.