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It is now clear that the plasma membrane does not represent the only platform for Ras signalling: genetically encoded fluorescent probes have revealed signalling on a variety of intracellular membranes, included the Golgi apparatus [10].
NMR-based metabonomics provides this alternative, as it integrates the responses of all different organs to the altered GHR signalling on a whole-body level and thus offers a direct, cost-effective and non-invasive avenue to monitor actual metabolic changes in a subject over several months.
To assess the impact of active Hh signalling on a very strong physiological TCR signal, we investigated thymocyte deletion by endogenous superantigens.
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FISH analysis demonstrated a specific hybridisation of COL7A1 cDNA on five chromosomes, one signal on each chromosome 3, corresponding to endogenous COL7A1, one signal on a chromosome 2, one on a chromosome 22, confirming the LM-PCR results, and revealed an additional signal on a chromosome 11 (Fig 5A).
In aposporous species, the ASGR-linked BACs were detected as strong signals on a single chromosome with one exception.
The referee is notified within one second by a vibration and visual signal on a watch.
Note that insider buying is a better bullish signal on a stock than insider selling is a bearish one.
Soon, Weber started reporting signals on a daily basis.
Nor does voting provide a feedback signal on a government's overall performance.
The orb receives a signal on a wireless frequency used by pagers.
The meeting is brought to an abrupt close when Claudia spots the abort signal on a passing car.
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