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2More and better education is associated to higher wages both in standard human capital models and in signalling models where education acts as a signal of valuable innate abilities.
As a consequence the effect of phosphatases are often also not studied in signalling models.
We demonstrate the power of our framework by analysis of the NF- κB and MAPK signalling models.
We showed, with realistic biochemical signalling models, that using this approach one is able to explore parameter space such that conditions can be found for which there is minimal, or maximal, noise.
The literature typically presents signalling models of charitable giving in the context of donors facing uncertainty regarding the quality of a beneficiary charity: government funding of a charity is seen as a signal of the quality of that particular organisation rather than of the cause the charity is supporting.
Rather than assume (as most signalling models do) that there are just two classes of people above and below average the authors start with three categories: high, medium and low ability.
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Thus we begin by observing that the Notch signalling model can be solved numerically using COMSOL.
Analysis of the MAPK signalling model.
The signalling model simulation simulates 10 ms of the glutamate signal.
In a later subsection we present analogous observation for a MAPK signalling model.
The various parameter values used in the signalling model are given in Table 5.
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