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These results underscore the concept that the phosphotyrosine motif and the PRR of M2 exert intertwined actions for the optimal manipulation of the B-cell signalling machinery.
Pilus-mediated adhesion and filament retraction participate in a signalling system in which Nme is capable of modulating the host cell signalling machinery through T4P [16].
Our study thus illuminates the network of interactions between core kinetochore components that provide the scaffold for subsequent loading of additional kinetochore proteins such as microtubule associated factors and components of the checkpoint signalling machinery.
Homologs of the Arabidopsis ABA signalling machinery were differentially expressed between rootstocks.
In principle, the detected target processes strongly resemble those of the light signalling machinery.
Several additional components of the downstream ethylene signalling machinery are known to undergo prevalent post-transcriptional regulation.
Additionally, neither ace1 nor cre1 or cpc1 are among the targets of the light signalling machinery in T. reesei.
Our results illustrate a remarkable evolutionary plasticity in interactions between mammalian GPCRs and C. elegans signalling machinery, spanning 800 million years of evolution.
Under caspase-limited conditions, the necroptotic cell signalling machinery is regulated by RIPK1, with the impact of scaffolding function as compared with kinase function still unclear.
Ethylene could accelerate ovule senescence, which implies the degradation of all tissues and cell organisation which, in turn, would disassemble the GA perception and signalling machinery.
Lack of components of the light signalling machinery causes considerably increased light responsiveness of transcript levels, likely caused by a light-dependent, positive effect on output pathways.
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