Sentence examples for signalling contributes from inspiring English sources

The unrestrained EGFR signalling contributes to malignant phenotype in a number of cancers including Malignant Mesotheliomas.

The timing of growth factor activity is critical for the initiation of mesendoderm formation from ESCs and paracrine signalling contributes to mesendoderm development.

As Lbe is activated in stalk myoblasts after overexpression of Arm Fig. 5H, I we speculate that Wg signalling contributes to this diversification process.

The findings reported herein suggest that altered BAFF signalling contributes to this phenotype and may act to enhance entry of self-reactive B cells into more mature B cell compartments.

To test this hypothesis, we employed gamma-secretase inhibitors to block Notch activity and overexpression of the Notch ligand Dll4 to address how Notch signalling contributes to the function of BM-PC in vitro and during the angiogenic response in cutaneous wound healing.

We found that the decreased cell proliferation and survival induced by N-cadherin overexpression was abrogated by N-cadherin blockade, which reverses N-cadherin-LRP5 interaction in osteoblasts [39] and was partly restored by Wnt3a, indicating that N-cadherin-LRP5 mediated alteration of canonical Wnt signalling contributes to the negative effect of N-cadherin on cell growth.

These results demonstrate that Eph receptor activation by ephrins can partially restore spine pruning in the Purkinje cell proximal dendritic domains of tetrodotoxin-treated cerebella in the absence of climbing fibre activity, suggesting that ephrin/Eph signalling contributes to the spine inhibitory effect mediated by active climbing fibres.

Some evidence suggests that dysregulated insulin signalling contributes to PCOS.

Inhibition of epidermal growth factor receptor (EGFR) signalling contributes to the therapy of colorectal cancer.

Bcr (B-cell receptor) signalling contributes to many important events in the immune system.

We also discuss the degree to which activated JAK/STAT signalling contributes to oncogenesis.