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We establish a performance evaluation framework, which contains per hop metrics for describing the router's signalling capability and per reservation metrics for characterising the overall performance of the reservation protocol.
For this reason, different nuclear-cytoplasmic trafficking of ERK1 and 2 would cause a differential signalling capability.
Signalling capability, therefore, is already recognised among the M13 family.
Hyper-IL-6 was more effective than IL-6 in suppressing proliferation in agreement with the enhanced signalling capability of this factor.
Given the known signalling capability of NEP, a close homologue of ECE-1, it can be speculated that heterodimerisation of ECE-1 isoforms may trigger intracellular signalling.
Even so, immature ovules promote better pollen tube guidance than heat-treated or fertilized ovules, suggesting that a basal signalling capability is established early and increases as the female gametophyte differentiates.
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We have provided computational, biochemical and functional evidence that ERK1 and 2 have different signalling capabilities.
As has been observed for other G protein-coupled receptors [12], interactions with additional intracellular signalling molecules (e.g. PDZ domain-containing adaptor proteins) modify the subcellular localization and the signalling capabilities of SSTRs [13], [14], [15].
Therefore, marsupials have probably evolved or maintained additional signalling capabilities in their CEACAM1-like proteins.
However, genes clearly do not act by themselves, or indeed they do not have catalytic or signalling capabilities.
The adhesive signalling capabilities, mainly studied for CYR61/CCN1 are of special relevance for tissue homeostasis in the bone and cartilage microenvironment [ 11, 13, 43].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com