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However, the signaling interaction is needed between the MDA and multicast source, which brings the extra network load.
Therefore, under a macro cell, the handover process is just simplified to the U-plane handover, which saves lots of control signaling interaction.
However, as deployment gets increasingly dense, the huge redundant control signaling interaction caused by frequent handovers between small and macro cells reduces the efficiency of heterogeneous networks.
Blood capillaries in 3D-iPSC CM tissues will also be important for in vitro toxicity assay of prodrugs because of the signaling interaction between cardiomyocytes and endothelial cells.
Given differential protein expression across tissues and developmental stages, the architecture and dynamics of signaling interaction proteomes is, likely, highly context dependent.
However, the underlying mechanisms of RAS and Wnt/β-catenin signaling interaction and their contribution to the pathogenesis of CKD have not been fully elucidated.
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The identified downstream signaling network comprises 575 proteins with 919 signaling interactions, as shown in Figure 2, which interacts with another 433 proteins via 4365 PPIs.
These binding activities are implicated in physiologic as well as pathologic events if errors in signaling interactions occur.
The function and development of cells rely heavily on the signaling interactions with the surrounding extracellular matrix (ECM).
Moreover, we observed reciprocal signaling interactions between FGCs and their gonadal niche cells, including activation of the bone morphogenic protein (BMP) and Notch signaling pathways.
It is worth mentioning that signaling interactions in control plane and performance analysis on MAC layer are the focuses in our following work.
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