Sentence examples for signaling actions from inspiring English sources

Mixtures of XEs, commonly found in contaminated environments, disrupt the signaling actions of physiological estrogens even more severely than do single XEs.

These signaling actions have been reduced to a simple activator-inhibitor feedback loop in computational modeling studies [ 22– 22].

The hypothalamus must have upward signaling actions to change learning and behavior, and indeed effects of leptin are seen at such levels (30).

Proinflammatory lipid mediators such as the eicosanoids compete against the signaling actions of newly discovered modified fatty acids that act to resolve inflammation.

36 The nucleocytoplasmic shuttling of IPMK and the identification of the nuclear receptor steroidogenic factor 1 as a new IPMK target also indicate the complexity of IPMK signaling actions.

Signaling actions of S1P can be executed within the intracellular space, as well as the extracellular space when it acts as a ligand of five G-protein coupled receptors (S1P1 S1P5) [ 34, 35].

The negative feedback genes are generally thought to functionally terminate the signaling action of the transcription factor.

This signaling action of cytosolic Hsp60 affects the induction of the two NF-κB target genes, Bfl-1/A-1 and MnSOD, and thus cell survival.

The signaling pathways activated by these interactions may influence such diverse phenomena as intracellular Ca2+ signaling action potentials and exocytosis of other potent mediators like nitric oxide, acetylcholine and prostaglandins [5].

87 While DPP-4 inhibitors do not affect the signaling action, there is a concern that inhibition of enzymatic action on regulatory peptides may produce unforeseeable AEs.

Another path of signaling action is activation of the RAS/RAF/MEK MAPK cascade resulting in cell growth and gene expression alterations expressed by the crosstalk between " Type II diabetes mellitus" and " MAPK signaling" pathways.